Mycobacterial Biofilms
نویسندگان
چکیده
منابع مشابه
Mycobacterial Biofilms: A Greasy Way to Hold It Together
Microorganisms growing on surfaces can form biofilms under certain conditions. In this issue of Cell, Ojha et al. (2005) investigate biofilm formation in mycobacteria. They identify new cell-wall components that are required for the formation of architecturally complex mature biofilms in these bacteria and the surprising involvement of a chaperone protein in this process.
متن کاملMycobacterial biofilms facilitate horizontal DNA transfer between strains of Mycobacterium smegmatis.
Conjugal transfer of chromosomal DNA between strains of Mycobacterium smegmatis occurs by a novel mechanism. In a transposon mutagenesis screen, three transfer-defective insertions were mapped to the lsr2 gene of the donor strain mc(2)155. Because lsr2 encodes a nonspecific DNA-binding protein, mutations of lsr2 give rise to a variety of phenotypes, including an inability to form biofilms. In t...
متن کاملIdentification of Bicarbonate as a Trigger and Genes Involved with Extracellular DNA Export in Mycobacterial Biofilms
Extracellular DNA (eDNA) is an integral biofilm matrix component of numerous pathogens, including nontuberculous mycobacteria (NTM). Cell lysis is the source of eDNA in certain bacteria, but the source of eDNA remains unidentified for NTM, as well as for other eDNA-containing bacterial species. In this study, conditions affecting eDNA export were examined, and genes involved with the eDNA expor...
متن کاملBiofilms
Our understanding of the virulence and pathogenesis of Francisella spp. has significantly advanced in recent years, including a new understanding that this organism can form biofilms. What is known so far about Francisella spp. biofilms is summarized here and future research questions are suggested. The molecular basis of biofilm production has begun to be studied, especially the role of extrac...
متن کاملMycobacterial infection.
Tuberculosis and leprosy are two well known mankind diseases that are caused by members of the genus Mycobacterium. When originally named in 1896, this genus contained the leprosy bacillus (Mycobacterium leprae) observed by Armour Hansen in 1874 and the tubercle bacillus (Mycobacterium tuberculosis) observed and cultured by Robert Koch in 1882. As time went by, other bacilli similar to those of...
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ژورنال
عنوان ژورنال: Microbiology Spectrum
سال: 2014
ISSN: 2165-0497
DOI: 10.1128/microbiolspec.mgm2-0004-2013